Fgf negative regulators control early chick somite myogenesis
نویسندگان
چکیده
منابع مشابه
Influence of experimental hypothyroidism on chick myogenesis.
The influence on chick myogenesis of hypothyroid status induced in ovo by methimazole was histologically (number and types of muscle fibers) and biochemically studied. A single injection of methimazole induced an hypothyroid status during embryogenesis, as shown by the plasma T4 levels which were separately assayed in male and female controls and treated embryos from day 12 of incubation to day...
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Evidence from a number of studies (e.g. Holtzer, 1964; Coon & Cahn, 1966; Konigsberg, 1963) has suggested that the differentiation of some types of cells in vitro may be influenced by environmental factors. Culture conditions can permit or prevent the phenotypic expression of characteristics already determined in the cells. The length of time involved in the stabilization of differentiation app...
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Vertebrate segmentation requires a molecular oscillator, the segmentation clock, acting in presomitic mesoderm (PSM) cells to set the pace at which segmental boundaries are laid down. However, the signals that position each boundary remain unclear. Here, we report that FGF8 which is expressed in the posterior PSM, generates a moving wavefront at which level both segment boundary position and ax...
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GDF11, a new member of the TGF-beta gene superfamily, regulates anterior/posterior patterning in the axial skeleton during mouse embryogenesis. Gdf11 null mice display skeletal abnormalities that appear to represent anterior homeotic transformations of vertebrae consistent with high levels of Gdf11 expression in the primitive streak, presomitic mesoderm, and tail bud. However, despite str...
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Chick embryos were treated in ovo and in vitro with L-phenylalanine from the intermediate streak stage (Hamburger & Hamilton stage 3, 12-13 h of incubation) to the 7-somite stage (H & H stage 9, 29-33 h of incubation). Treatment in ovo resulted in a large number of embryos developing somite blocks, i.e. imperfectly segmented somites. In embryos treated at an early developmental stage (12-21 h o...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2014
ISSN: 1471-2164
DOI: 10.1186/1471-2164-15-s2-p18